Coccidiosis in Livestock, Poultry, Companion Animals, and Humans
Coccidiosis is one of the most important diseases of livestock, particularly poultry, with billions of dollars spent on prevention worldwide. The disease is so important and pervasive that until recently, all poultry feed was medicated with coccidiostats, mainly antibiotics. With the rapid development of drug resistance, the search is on for alternative methods of control of coccidiosis in poultry. With chapters authored by internationally renowned scientists, this book covers coccidiosis in all major livestock species, including cattle, sheep, and goats. Special emphasis is given to poultry coccidiosis given the significant economic impact, and another chapter looks at intestinal coccidiosis in humans, including Cyclospora. Chapters discuss techniques, molecular biology, host-pathogen immunobiology and immunoprophylaxis, genetics and genomics, biology, and chemotherapy.
Despite an explosion of research in the last 40 years, there has been no new book published discussing conventional coccidiosis for more than 25 years. This comprehensive review therefore answers an urgent need for a book dealing exclusively with conventional coccidia (Cystoisospora, Cyclospora). It provides concise, authoritative, up-to-date information on coccidiosis, with particular attention given to research in the last 28 years.
This book is essential reading for any practitioner or researcher involved in livestock production, including biologists, veterinarians, parasitologists, and researchers from government, academia, and industry.
Coccidiosis in Livestock, Poultry, Companion Animals and Humans is a long needed update and review for this group of clinically important protozoan parasites that infect a wide variety of hosts. It’s been 25 years since the coccidia were thoroughly reviewed with updated information so it’s timely and needed. The group of internationally recognized authors and subject matter experts have updated important aspects about Coccidiosis including detailed chapters on their biology, phylogeny, immunity, vaccination, modern molecular biology techniques, anticoccidial drugs, and new information on the coccidia of cattle. Coccidiosis in Livestock, Poultry, Companion Animals and Humans will be a must have comprehensive resource for a wide range of global scientific disciplines for upper level undergraduate and graduate students, and researchers that include veterinary parasitologists, veterinarians, physicians, clinicians, and animal and poultry scientists.-
-- Daniel E. Snyder, Veterinary Parasitology Consultant at ‘Daniel E. Snyder, DVM, PhD Consulting, LLC.’ October 2019
This book focuses on the genera Eimeria, Cyclospora and Cystisospora, which are apicomplexan parasites, known as conventional coccidia, and cause coccidiosis. Coccidiosis is one of the most important diseases of livestock, particularly poultry, but occurs also in many other farm and companion animals, as well as in humans. Coccidiosis has a huge economic impact, and represents a constant threat to the food supply. The extensive use of coccidiostats, especially against Eimeria in poultry, has led to widespread drug resistance, and this problem needs to be solved in the years to come, as there are many challenges ahead in order to ensure food security, but also food safety, for an ever-growing population on this planet. A plethora of studies on different aspects of coccidian biology, phylogeny, pathogenesis and treatment and prevention strategies have been carried out and published during the last 20-30 years, and it has become difficult to keep track and maintain an overview of the research developments in the field. Thus, this book summarizes in a concise and very structured manner the current knowledge on coccidiosis caused by conventional coccidia, and as such fills an important gap.
The driving force behind this book has been Dr. Jitender P. Dubey, which is clearly one of the most eminent parasitologists on this planet, and also known for his excellent books on Toxoplasma, Cryptosporidium, Sarcocystis and Neospora. Here, Dr. Dubey recruited scientists of high international reputation from all over the world to contribute chapters on the basic biology of coccidia, phylogeny, host immunity, vaccination, genomics, transcriptomics and proteomics, and on the current state of anti-coccidial drugs. These seven chapters provide an excellent and up-to-date overview on the covered subjects. The following chapters are dedicated to coccidiosis in the different major livestock species, including cattle, water buffaloes, pigs, sheep, goats, and most important, poultry. However, also other host species are covered, including camelids, rabbits, turkeys, ducks, horse and other equids, dogs, cats, and also humans. In these chapters the reader will encounter concise information on the different species of coccidia found in the different host species, the life cycle and morphological features, data on prevalence, on the pathogenesis, diagnosis, management and treatment options.
The book also contains stunning illustrations, showing the morphological, histological and structural features of the different coccidia, and how infections affect their hosts and cause disease. In addition, many Tables are provided that summarize all this information in a concise and clear manner. Overall, I believe that this book represents an invaluable, highly useful resource and "must-have" for all interested in coccidian parasites, including students, biologists, veterinarians, parasitologists, government, academia and industry.
-- Andrew Hemphill, Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Universität Bern, Switzerland